Quantitative Comparison Of Three Optical Coherence Tomography Angiography Devices In Chorioretinal Disease

Purpose: Optical coherence tomography angiography (OCT-A) has emerged as a novel tool for non-invasive imaging and evaluation of the retinal microvasculature. There is little existing literature that compares OCT-A metrics across different OCT-A devices in chorioretinal diseases. The aim of this study was to compare OCT-A metrics from three OCT-A platforms: Optovue RTVue-XR, Topcon DRI-OCT Triton Swept-Source OCT, and Zeiss Cirrus 5000-HD-OCT Angioplex.Methods: Subjects were scanned on each of the three OCT-A devices. Two investigators independently measured foveal avascular zone (FAZ) area. Superficial capillary plexus (SCP) and deep capillary plexus (DCP) vessel densities (VD) were calculated from binarized images utilizing ImageJ software. Interclass correlation coefficient (ICC) and repeated measures ANOVA were performed for statistical analysis.Results: Thirteen eyes of seven …