Characterization of β-cyclodextrin/myrtenol complex and its protective effect against nociceptive behavior and cognitive impairment in a chronic musculoskeletal pain model.

Carbohydrate Polymers(2020)

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摘要
•β-cyclodextrin/myrtenol (β-CD/MYR) complex was done by slurry complexation method.•β-CD/MYR complex reduced mechanical hyperalgesia in animal model.•β-CD/MYR complex showed anxiolytic-like effect in animal model of fibromyalgia.•β-CD/MYR complex prevented cognitive impairment caused by acid saline injection.•These effects seemed to be related to the maintenance of redox homeostasis.
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CSF,DSC,EPMT,NOR,OFT,PM,KN,SC,SEM,XRD
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