Long non-coding RNA MINCR aggravates colon cancer via regulating miR-708-5p-mediated Wnt/β-catenin pathway.

Yang Yu,Zhuo Chang,Chao Han,Lingling Zhuang,Chongzhi Zhou,Xiaosheng Qi,Zhihai Peng

Biomedicine & Pharmacotherapy（2020）

引用 26|浏览11

暂无评分

摘要

•MINCR knockdown hampered proliferation, migration, invasion and EMT process in CC cells.•MINCR mediated CC procession via the regulation of Wnt/β‐catenin pathway.•MINCR activated Wnt/β‐catenin pathway by targeting miR-708−5p/CTNNB1 axis.•MINCR silence suppressed CC growth and metastasis in vivo.

查看译文

关键词

Colon cancer,MINCR,miR-708-5p,CTNNB1,Wnt/β‐catenin pathway

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要