External trigeminal nerve stimulation for drug resistant epilepsy: a randomized controlled trial.

Francisco Gil-López,Teresa Boget,Isabel Manzanares,Antonio Donaire,Estefanía Conde-Blanco,Eva Baillés,Luis Pintor,Xavier Setoaín,Núria Bargalló,Judith Navarro, Jordi Casanova,Josep Valls,Pedro Roldán,Jordi Rumià, Georgina Casanovas,Gema Domenech,Ferrán Torres,Mar Carreño

Brain Stimulation（2020）

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摘要

•External trigeminal nerve stimulation (ETNS) is effective to treat focal DRE.•Percentage of responders at 12 months was 50% in ETNS group.•Temporal epilepsy responded better than frontal epilepsy (55.56% vs. 45.45%).•ETNS was non-invasive, safe, well tolerated, and improved quality of life.•The role of ETNS compared to other neurostimulation techniques is still undefined.

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关键词

Trigeminal nerve stimulation,Epilepsy,Epileptogenic zone,Neurostimulation,Clinical trial

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