The Ras-ERK1/2 signaling pathway regulates H3K9ac through PCAF to promote the development of pancreatic cancer.

Life Sciences（2020）

引用 6|浏览19

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摘要

Ras ERK1/2 promotes pancreatic carcinogenesis cell movement, through down-regulating H3K9ac via MDM2 mediated PCAF degradation.

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关键词

Ras-ERK pathway,H3K9ac,HDAC1,PCAF,ASPC-1 cell

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