Original protocol and modifications

Optimal strategies for identifying kidney disease in diabetes: properties of screening tests, progression of renal dysfunction and impact of treatment–systematic review and modelling of progression and cost-effectiveness(2014)

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Aims and objectivesAimTo evaluate the benefits and harms of ACE inhibitors and ARB in comparison with placebo, other antihypertensive agents or no treatment in patients with diabetes with and without kidney disease. The review will focus on impact on overall mortality, renal and cardiovascular outcomes.Objectives
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