Antibodies in sera from multiple sclerosis patients recognize Trichinella spiralis muscle larvae excretory–secretory antigens

Alisa Gruden-Movsesijan,Jelena Drulovic,Tatjana Pekmezovic,Ivana Mitic,Jelena Cvetkovic,Marija Gnjatovic,Ljiljana Sofronic-Milosavljevic

Immunobiology（2020）

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摘要

•Immunoglobulins from sera of multiple sclerosis patients recognize molecules from Trichinella spiralis ES L1 antigens.•The reaction with 45, 49 and 58 kDa proteins was associated with MS.•ES L1 antigens and MS-related autoantigens could share structural or sequence homology.

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关键词

Multiple sclerosis,Trichinella spiralis antigens,Molecular mimicry

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