Organoid modelling identifies that DACH1 functions as a tumour promoter in colorectal cancer by modulating BMP signalling
EBioMedicine, pp. 1028002020.
BMP signalling pathwayColorectal cancerDACH1OrganoidStem cells
Together, our study highlights DACH1 as an integral regulator of BMP signalling during intestinal tumorigenesis, and DACH1 could be a potential prognostic marker and therapeutic target for colorectal cancer patients.
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