Serratane triterpenoids from Lycopodium complanatum and their anti-cancer and anti-inflammatory activities.

Wenhao Zhou,Fenghua Kang, Lili Huang,Jing Li,Wenxuan Wang,Ling Xiao, Qiwan Wen,Xia Yu,Yangrui Xu,Zhenxing Zou,Hui Zhou,Hui Zang,Siwei Chen,Kangping Xu

Bioorganic Chemistry（2020）

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摘要

•Eight new serratane triterpenoids were isolated from Lycopodium complanatum.•The absolute configurations of 6–8 were determined by DFT GIAO 13C NMR calculations.•The cytotoxic activities were assessed on seven different human cancer cell lines.•All compounds could inhibit the NO release of RAW 264.7 cells induced by LPS.

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关键词

Lycopodium complanatum,Serratane triterpenoids,Anti-cancer activities,Anti-inflammatory effects

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