LEISHMANICIDAL ACTIVITY in vivo OF A MILTEFOSINE DERIVATIVE IN Mesocricetus auratus

Acta Tropica(2020)

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摘要
•C11 showed leishmanicidal activity in the spleen and liver from Mesocricetus auratus•Cytokine profile expression resulted in resistance to leishmaniasis in the C11 group•C11 preserved the spleen and liver architecture in the experimental leishmaniasis
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关键词
Miltefosine derivative,experimental treatment,visceral leishmaniasis,immune response
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