LncRNA MEG3-210 regulates endometrial stromal cells migration, invasion and apoptosis through p38 MAPK and PKA/SERCA2 signalling via interaction with Galectin-1 in endometriosis.

•MEG3-210 transcript expressed lower in eutopic endometrium and endometrial stromal cells (ESCs) of patients with endometriosis when compared with patients without endometriosis.•Downregulation of MEG3-210 promoted ESCs migration, invasion and anti-apoptosis, overexpression of MEG3-210 exerted opposite effects.•Effects of MEG3-210 downregulation on ESCs were through activating p38 MAPK signaling and inhibiting PKA/SERCA2 signaling via interaction with Galectin-1 in endometriosis.