The miR-532-3p/Chrdl1 axis regulates the proliferation and migration of amniotic fluid-derived mesenchymal stromal cells.

Biochemical and Biophysical Research Communications(2020)

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摘要
•Chrdl1 is expressed at lower levels in amniotic fluid mesenchymal stromal cells derived from the early stages of pregnancy.•Chrdl1 suppresses the proliferation and migration of amniotic fluid derived-mesenchymal stromal cells.•miR-532-3p targets Chrdl1 to promote proliferation and migration of amniotic fluid derived-mesenchymal stromal cells.
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关键词
Mesenchymal stromal cell,Amniotic fluid,Embryo development,Proliferation,Migration,Chrdl1
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