Association between the -2548G/A polymorphism of the leptin gene and antipsychotic-induced weight gain: Analysis of the CATIE sample and meta-analysis.

Progress in Neuro-Psychopharmacology and Biological Psychiatry(2020)

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摘要
•The LEP -2548G/A polymorphism was not associated with AIWG in a sub-sample from the CATIE study.•The LEP -2548G/A polymorphism was not associated with AIWG in the meta-analysis.•The LEP -2548G/A polymorphism may influence AIWG in first-episode schizophrenia patients.
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关键词
Antipsychotic-induced weight gain (AIWG),Clinical antipsychotic trials of intervention effectiveness (CATIE),Leptin,Meta-analysis,Schizophrenia
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