Prepregnancy body mass indexes are associated with perinatal outcomes in females with preeclampsia

EXPERIMENTAL AND THERAPEUTIC MEDICINE(2020)

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摘要
The present study aimed to determine the clinical characteristics and perinatal outcomes of females with severe preeclampsia according to their pre-pregnancy body mass index (BMI). Data from 233 patients with severe preeclampsia were reviewed from the Inpatient Obstetrics Department. The data were divided into 3 groups according to the patients' pre-pregnancy BMI: Normal (BMI of 18-25 kg/m(2); n=134); underweight (BMI <18 kg/m(2); n=15); and overweight and obese (BMI >25 kg/m(2); n=84). The incidence of dyslipidemia, amniotic fluid abnormalities and neonatal hospitalizations in the group of females who were overweight or obese before pregnancy were higher than those in the other groups (all P<0.05). In conclusion, the presence of dyslipidemia, excessive weight and obesity prior to pregnancy in patients with severe preeclampsia was associated with maternal and perinatal outcomes.
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关键词
preeclampsia,obesity,oxidative stress,free fatty acids
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