Association of history of adverse childhood experiences with irritable bowel syndrome (IBS) in individuals with mood disorders.

•Mood disorders are associated with an increased prevalence of irritable bowel syndrome (IBS) and history of adverse childhood experiences (ACEs)•In total, 69 of the 498 mood disorder participants reported a diagnosis of IBS (13.8%)•BD was associated with elevated rates of IBS compared to MDD•History of childhood sexual abuse was associated with increased rates of IBS in mood disorder participants•In the subgroups, history of sexual abuse was associated with an increased prevalence of IBS in BD, but not in MDD.