The evolving indications of KD therapy.

•The use of the KD has evolved according to the types of seizures and epilepsy and etiology.•The KD works well in certain epilepsy syndromes, especially the epileptic encephalopathies.•The KD has been increasingly used as therapy for refractory and super-refractory status epilepticus.•KD may be indicated at any age from neonates to adults.