Gene mutations related to rifampin resistance of tuberculosis in northwest of Iran

Pourya Gholizadeh,Tala Pourlak,Mohammad Asgharzadeh, Mohammad Hossein Soroush Barhagi,Sepehr Taghizadeh,Mohammad Ahangarzadeh Rezaee, Ahad Zarei,Elghar Soltani,Rasoul Hosseinpour,Hossein Samadi Kafil

Gene Reports（2020）

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摘要

•Rifampicin-resistant M. tuberculosis is a public health threat worldwide.•The frequencies of the mutations in the RRDR region of the rpoB gene were low.•Most of the resistance isolates were collected from patients originated from Azerbaijan.•Policies to restrict infection distribution in the regions are important.

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关键词

TB,WHO,MDR/RRTB,rpoB,Emb,inhA and KatG,RRDR,NALC-NaOH,CDC,CTAB

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