Presence, Volume, and Location of New Ischemic Injury on MRI in Stroke Patients Who Undergo PFO Closure Compared to Patients Treated Medically: An Analysis of the REDUCE Trial

Steven R. Messe,Guray Erus,Michel Bilello,Christos Davatzikos,Grethe Andersen,Helle Iversen,Risto O. Roine,Christina Sjostrand,Howard C. Herrmann,John F. Rhodes,Lars Sondergaard,Scott E. Kasner

Stroke（2020）

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Background: Randomized PFO closure trials have used open-label endpoint ascertainment, which may increase the risk of bias and undermine confidence in the conclusions. The Gore REDUCE Trial prospec...

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