Logic-based analysis of gene expression data predicts association between TNF, TGFB1 and EGF pathways in basal-like breast cancer

Methods(2020)

引用 6|浏览54
暂无评分
摘要
•Pathway Logic is a rewriting-logic-based system for modeling biological pathways.•We propose a novel framework to integrate Pathway Logic and gene expression data.•TCGA dataset was analyzed to explain differences in breast cancer subtypes.•Our system detected subtype-specific paths from key receptors to transcription factors.
更多
查看译文
关键词
Breast cancer,Biological pathway,Gene expression,Pathway logic,Transcription factor
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要