Aberrant corin and PCSK6 in placentas of the maternal hyperinsulinemia IUGR rat model.

Zaid Abassi,Safa Kinaneh,Galina Skarzinski,Einat Cinnamon,Yoav Smith,Michael Bursztyn,Ilana Ariel

Pregnancy Hypertension（2020）

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摘要

•Hyperinsulinemic dams (HD) developed pregnancy-induced hypertension (PIH), along lower placental and fetal weights.•Corin expression and abundance are significantly decreased in the placenta, but not in the mesometrial triangle of HD.•Placental PCSK6 immunoreactivity are lower in HD, concomitantly with enhanced proANP levels.

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