Preliminary Assessment of Nanopore-based Metagenomic Sequencing for the Diagnosis of Prosthetic Joint Infection.

•mONS can provide rapid, accurate information on pathogenic strains in PJI samples.•The species identified by mONS from fresh samples corresponded with both routine culture and mNGS results.•This study showed proof of concept that mONS can function as a rapid, accurate tool in PJI diagnostic microbiology.