Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model Christophe Fromont , Alessio Atzori , Divneet Kaur , Lubna Hashmi , Graziella Greco , Alejandro Cabanillas , Huy Van Nguyen , D. Heulyn Jones , Miguel Garzon , Ana Varela , Brett Stevenson , Greg P. Iacobini , Marc Lenoir , Sundaresan Rajesh , Clare Box , Jitendra Kumar , Paige Grant , Vera Novitskaya , Juliet Morgan , Fiona J. Sorrell , Clara Redondo , Andreas Kramer , C. John Harris , Brendan Leighton , Steven P. Vickers , Sharon C. Cheetham , Colin Kenyon , Anna M. Grabowska , Michael Overduin , Fedor Berditchevski , Chris J. Weston , Stefan Knapp , Peter M. Fischer , Sam Butterworth JOURNAL OF MEDICINAL CHEMISTRY（2020）
关键词
Insulin Signaling, Metabolic Regulation
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