Investigation of Anomalous Charge Variant Profile Reveals Discrete Ph-Dependent Conformations and Conformation-Dependent Charge States Within the CDR3 Loop of a Therapeutic Mab.
mAbs（2020）
Key words
pH-dependent conformation,charge heterogeneity,conformational equilibrium,HC-CDR3,therapeutic monoclonal antibody,cation exchange chromatography,hydrophobic interaction chromatography,surface plasmon resonance
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined