Poloxamer modified florfenicol instant microparticles for improved oral bioavailability.

Colloids and Surfaces B: Biointerfaces(2020)

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摘要
•The modified O/O emulsion solvent evaporation method produces high-yield florfenicol instant microparticles.•Improving the oral bioavailability of florfenicol by developing florfenicol instant microparticles.•Polymer poloxamer 188 covers the surface of the microparticles to improve the solubility of the poorly soluble drug florfenicol.
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关键词
Florfenicol,Surfactant,Microparticle,Bioavailability
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