Human monocyte-derived dendritic cells as an in vitro alternative model cell to evaluate the immunotoxicity of 2, 4-Dinitrochlorobenzene.

Toxicology Letters(2020)

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摘要
•Human monocyte-derived DC is an attractive cell to evaluate DNCB immunotoxicity.•Blood center can provide stable leukocyte and greatly reduce the cost to obtain DC.•Human monocyte-derived DCs had more comprehensive immune response capacity than THP-1.
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关键词
Sensitization,Dendritic cells,DNCB,THP-1,Immunotoxicity
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