A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility.

Meilin Wei,Fengjie Huang,Ling Zhao,Yunjing Zhang,Wei Yang,Shouli Wang,Mengci Li,Xiaolong Han,Kun Ge,Chun Qu,Cynthia Rajani,Guoxiang Xie,Xiaojiao Zheng,Aihua Zhao,Zhaoxiang Bian,Wei Jia

EBioMedicine（2020）

引用 117|浏览83

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摘要

Our study highlights that dysregulated BA signaling mediated by gut microbiota contributes to obesity susceptibility, suggesting modulation of BAs could be a promising strategy for obesity therapy.

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关键词

Obesity,Bile acids,Gut microbiota,Energy expenditure,GLP-1,UCP1

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