Identification of nsSNPs of transcription factor E2F1 predisposing individuals to lung cancer and head and neck cancer

Sanjay Singh,Ragothaman M. Yennamalli,Manish Gupta,Harish Changotra

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis（2020）

引用 7|浏览4

暂无评分

摘要

•This study identified six highly deleterious nsSNPs (C227F, R252H, V295D, C298Y, R56W, and Y59C) of E2F1 gene.•The Case-control study showed that R252H increase ∼2-5 fold risk of LC and HNC in Indian.

查看译文

关键词

E2F1,Missense mutations,rs3213172C/T,Lung cancer,Head and neck cancer

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要