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Discovery of GS-9688 (selgantolimod) As a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B

Richard L. Mackman,Michael Mish,Gregory Chin,Jason K. Perry,Todd Appleby,Vangelis Aktoudianakis,Sammy Metobo,Peter Pyun,Congrong Niu,Stephane Daffis,Helen Yu,Jim Zheng,Armando G. Villasenor,Jeff Zablocki,Jason Chamberlain,Haolun Jin,Gary Lee, Kimberley Suekawa-Pirrone,Rex Santos,William E. Delaney,Simon P. Fletcher

Journal of Medicinal Chemistry（2020）

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