Reply to Letter to the Editor.

Reply: We would like to thank Dr Monachesi and coworkers for their interest in our recent study on the analytical performance of antitissue transglutaminase (atTG) chemiluminescence immunoassay and the enzyme-linked immunosorbent assay to monitor children with celiac disease after the start of gluten-free diet (1). The group of Ancona strengthens our findings in this setting, showing a similarly slow trend to normalization of atTG measured by another commercially available immunoassay (fluorescence enzyme immunoassay). Furthermore, in agreement with our results, they find that younger age at diagnosis, male sex, and lower baseline atTG are predictors of earlier atTG normalization. We definitely agree with their suggestion to use the same analytical technique for the diagnosis and the follow-up of children with celiac disease on gluten-free diet, and we believe this issue should be taken into account in the future societal guidelines on the follow-up of these patients.