Coexisting overexpression of STOML1 and STOML2 proteins may be associated with pathology of oral squamous cell carcinoma.

Daiwei Wang,Hong Qi,Ang Li, Fang Deng,Ying Xu,Zhangli Hu,Qiong Liu,Yun Wang

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology（2020）

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摘要

Our results indicated that overexpression of STOML1 and STOML2 was significantly associated with T1 and T2 stages of OSCC. STOML1 and STOML2 were mainly co-localized at the cell membrane and the cytoplasm. These findings suggested that either STOML1 or STOML2 may play critical roles in OSCC development and may serve as potential diagnostic biomarkers and therapeutic targets.

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