Possible link of genetic variants to autoimmunity in GAD-antibody-associated neurological disorders.

Journal of the Neurological Sciences(2020)

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摘要
•In patients with GAD-antibody associated disorders.•Autoimmune disorders co-occur suggesting genetic risk factors.•Haplotype DRB1*15:01:01 ~ DQA1*01:02:01 ~ DQB1*05:02:01 was not detected in our cohort.•No typical phenotype of autoimmune lymphoproliferative syndrome was observed.•Validation of observed genetic variants in genome wide studies is recommended.
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关键词
GAD65,Autoantibodies,Neurological disorders,Genetic variants
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