Prognostic value of perioperative red blood cell transfusion and anemia on survival and recurrence in oral squamous cell carcinoma.

Gerrit Spanier, Janika Böttcher,Michael Gerken,René Fischer, Gabriel Roth,Petra Lehn,Christoph Klingelhöffer,Johannes K Meier,Alessia Fraccaroli,Johanna Tischer,Tobias Ettl,Monika Klinkhammer-Schalke,Torsten E Reichert,Steffen Spoerl

Oral Oncology（2020）

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摘要

•Preoperative anemia is a negative predictor on survival and recurrence in OSCC.•Same for perioperative red blood cell transfusion (RBT) in a dose-dependent manner.•Unfavourable effects are mainly seen in perioperative RBT of non-anemic patients.•Transfusion strategy should be adapted depending on anemia status in OSCC patients.

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关键词

Oral squamous cell carcinoma,Oral cancer,Anemia,Transfusion,Survival,Transfusion-related immunomodulation,TRIM

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