GPR17 Plays a Role in Ischemia-induced Endogenous Repair of Immature Neonatal Cerebral White Matter.

Mao Feng-Xia,Chen Hui-Jin,Qian Long-Hua,S Buzby Jeffrey

Brain Research Bulletin（2020）

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摘要

•GPR17 plays a role in ischemia-induced endogenous repair of immature WM.•Ischemia-induced overexpression of GPR17 increased glial progenitors.•GPR17 gene silencing suppressed ischemia-induced glial progenitors proliferation.•which might provide a potential therapeutic target for immature WM injury.

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关键词

PVL,WM,GPR17,OGD,OL,IB4,GFAP,NeuN

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