A Novel Case Of Transcatheter Mitral Valve-In-Valve Replacement Using Mi-Thos (Tm) System

Transcatheter mitral valve replacement (TMVR) has become an alternative to surgical mitral valve replacement for the treatment of patients with severe mitral insufficiency (MI) who are at very high or prohibitive surgical risk.[1] Because of impaired left ventricular dysfunction and previous cardiac surgery, some aged patients with degenerated bioprosthetic mitral valve and mitral regurgitation were refused to redo surgery.[2] Increasing demand are required for minimally invasive treatment of these patients.Hundreds of patients worldwide have been treated with a transcatheter mitral valve-in-ring or valve-in-valve procedure using transcatheter aortic valve.[3] However, rare case of transcatheter mitral valve-in-valve/ring replacement using transcatheter mitral valve system was reported.Here, we reported a successfully case of transcatheter mitral "valve-in-valve" replacement for the treatment of bioprosthetic mitral valve degeneration and severe regurgitation with domestic MithosTM valve.