Size Measurement of Extracellular Vesicles and Synthetic Liposomes: The Impact of the Hydration Shell and the Protein Corona.

Zoltán Varga,Bence Fehér,Diána Kitka,András Wacha,Attila Bóta,Szilvia Berényi,Vitaliy Pipich,Jean-Luc Fraikin

Colloids and Surfaces B: Biointerfaces（2020）

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摘要

•Novel non-optical methods are used to characterize the size of EVs and liposomes.•Sizes from light scattering and MRPS reveal the thickness of the hydration layer.•VSANS combined with MRPS describes the protein corona and the PEG-layer.

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关键词

exosome,microparticle,liposomal drug delivery,small-angle neutron scattering,microfluidic resistive pulse sensing

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