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Structure-Guided Directed Evolution of a Carbonyl Reductase Enables the Stereoselective Synthesis of (2S,3S)-2,2-Disubstituted-3-hydroxycyclopentanones via Desymmetric Reduction

ORGANIC LETTERS(2020)

引用 21|浏览22
关键词
stereoselective synthesis,carbonyl reductase,desymmetric reduction,structure-guided
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