Nitric Oxide Inhalation is Associated with Decreased Incidence of Acute Rejection after Cardiac Transplantation

iNO-treated patients were sicker pre- and postoperatively compared to patients not receiving iNO. Despite iNO-patients being overall sicker, iNO-treatment associated with less rejections. Our findings suggest that iNO may have some long-term cardioprotective effects after HTx. In ISHLT 2020 meeting we aim to present also results on the effect of iNO on early inflammatory cell influx to the graft, and on changes in cardiac transcriptome using IHC and next-generation sequencing from cardiac biopsies.