RGD-modified ZnO nanoparticles loaded with nitric oxide precursor for targeted cancer therapy

Huiyu Ding,Liying Wang,Lin Zhang,Baohua Zhu, Lili Hou, Guicheng Huang,Ziqing Xu

Chemical Physics Letters(2020)

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摘要
•PSF@ZnO-RGD with stimuli responsibility was prepared via a step-by-step strategy.•Intracellular stimuli triggered release of Zn2+ ions and NO from PSF@ZnO-RGD.•Synergistic cancer therapy was achieved by the release of Zn2+ ions and NO.
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关键词
Zinc oxide,Nitric oxide,Tumor targeting,Cancer therapy
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