A Multi-Center Study of BAL CXCR3 Chemokines during Allograft Injury after Lung Transplantation

M.Y. Shino,R.M. Elashoff,N. Li,J.L. Todd,M.L. Neely, H. Kopetskie,M. Sever,J. Kirchner, C.W. Frankel,L.D. Snyder,E.N. Pavlisko,T. Martinu,L.G. Singer,W. Tsuang, M. Budev, P.D. Shah,N. Williams, M. Robien,J.M. Reynolds,S.M. Palmer,S.S. Weigt, J.A. Belperio

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2020）

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摘要

We demonstrate for the first time in a multicenter study, CXCR3 chemokine elevations during episodes of acute allograft injury. These findings support the association of CXCR3 chemokines during episodes of AR, LB and ALI, and may potentially offer novel therapeutic targets to prevent and treat these deleterious events.

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