Perfusate Metabolite Profiles in Ex Vivo Lung Perfusion Predict Graft Quality of Lungs Donated after Circulatory Death

C. Yang,C. Baciu, M. Hsin, A. Gower, J. Shin,X. Gao,M. Chen,M. Cypel, S. Keshavjee,M. Liu

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2020）

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摘要

We identified significantly altered metabolites in DCD lungs that distinguish between good and poor recipient outcomes. Future biomarker validation via a larger sample size is necessary prior to their use to optimally select post-EVLP DCD donor lungs for transplantation.

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