Dosing and Outcomes of Conversion to Extended-Release Tacrolimus in Lung Transplant Recipients

C.T. Doligalski,K.S. Walter, R.A. Evans, C.M. White,S. Krishnan, R.D. Coakley,L.J. Lobo

JOURNAL OF HEART AND LUNG TRANSPLANTATION（2020）

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摘要

Conversion from IR-Tac to LCP-Tac in LTRs was successful in this limited series. Most LTRs converted for tremor saw improvement. We observed decreases in dose requirements, however not to the degree recommended by package labeling (20%). Tac variability remained consistent with conversion. Further research is needed to determine the long-term clinical impact of conversion.

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