Pregnancy outcomes of a giant primary ovarian leiomyoma in the first trimester

Primary ovarian leiomyoma is a rare type of benign neoplasm. Ovarian leiomyoma cases until a recent date usually showed favorable pregnancy outcomes. Contrary to others, the present authors report a case of a nine-week miscarriage with a giant primary ovarian leiomyoma. This neoplasm originated from the ovary with estrogen secreted by the endocrine organs. Hormone secretion is increased during pregnancy, particularly in the first trimester, it is supposed that it stimulated growth and progression of the mass. A close examination in adnexa is necessary at prenatal check.