A renewable DNA biosensor for sensitive detection of DNA methyltransferase activity based on cascade signal amplification

Yunlong Liu,Yuanbiao Tu,Haiping Wu, Hang Zhang,Honghong Chen,Guohua Zhou,Peng Wang,Yueqing Gu

Sensors and Actuators B: Chemical（2020）

引用 11|浏览10

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摘要

•A structure recognition-based signal amplification was used for DNA MTase activity assay.•DNA polymerase extension reaction was used to regenerate the biosensor.•The renewed biosensor showed good analytical performance.

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关键词

DNA methyltransferase activity,Invasion reaction,Signal amplification,Renewable biosensor,Fluorescence detection

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