Intermittent theta-burst stimulation moderates interaction between increment of N-Acetyl-Aspartate in anterior cingulate and improvement of unipolar depression

Maxim Zavorotnyy,Rebecca Zöllner, Henning Rekate,Patricia Dietsche,Miriam Bopp,Jens Sommer,Tina Meller,Axel Krug,Igor Nenadić

Brain Stimulation（2020）

引用 19|浏览3

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摘要

•First controlled 1H-MRS study of iTBS effects in major depression.•ITBS is know to be associated with favorable clinical improvement.•If iTBS applied, higher NAA concentrations in ACC predict favorable BDI reduction.•Prefrontal iTBS might act through modulation of ACC neuronal viability.

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关键词

Unipolar major depression,Proton magnetic resonance spectroscopy,N-Acetyl-aspartate,Choline-containing compounds,Anterior cingulate cortex,Non-invasive brain stimulation,Intermittent theta-burst stimulation

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