Telacebec (Q203), a New Antituberculosis Agent.

NEW ENGLAND JOURNAL OF MEDICINE(2020)

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摘要
Telacebec (Q203) is a novel drug that targets Mycobacterium tuberculosis cellular energy production through inhibition of the mycobacterial cytochrome bc1 complex. This proof-of-concept study evaluated the bactericidal activity of telacebec over a period of 14 days in patients with newly diagnosed, drug-susceptible pulmonary tuberculosis.
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