Bis(1,3-Dimethylimidazolidinone) Hydrotribromide (DITB) Promoted Multicomponent Reaction for the Synthesis of Highly Functionalized Piperidines
Heterocycles(2020)
摘要
A convenient and efficient method has been developed for the synthesis of highly functionalized piperidines via three-component, one-pot domino reaction of beta-ketoesters, aromatic aldehydes, and anilines in the presence of catalytic amount of bis(1,3-dimethylimidazolidinone) hydrotribromide (DITB) in ethanol at room temperature.
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关键词
highly functionalized piperidines,multicomponent reaction,hydrotribromide,synthesis
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