Electroacupuncture improves cognitive deficits and insulin resistance in an OLETF rat model of Al/D-gal induced aging model via the PI3K/Akt signaling pathway.

Xinyu Huang,Kangbai Huang,Zhaowei Li, Dongyan Bai,Yan Hao,Qinglong Wu,Wei Yi,Nenggui Xu,Youcan Pan,Liang Zhang

Brain Research（2020）

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摘要

•EA could improve cognitive function in AD rat models.•EA could improve insulin resistance in AD rat models.•The PI3K/Akt path way is involved in the effects of EA in AD.

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关键词

Acupuncture,Insulin resistance,Alzheimer’s disease,β-Amyloid,Ostuka Long-Evans Tokushima Fatty rats

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