Outcomes of Laparoscopic Heller Myotomy for Achalasia: 22-Year Experience

Journal of Gastrointestinal Surgery(2020)

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摘要
Introduction Laparoscopic Heller Myotomy is the most effective treatment of achalasia. We examined the durability of symptomatic relief, with and without fundoplication. Methods A single institution database between 1995 and 2017 was reviewed. Achalasia symptom severity was assessed by Eckardt scores (ES) obtained at 3-time points via patient questionnaire. Primary outcome was treatment success defined as ES of < 3. Results Completed surveys were returned by 130 patients (median follow-up of 6.6 years). A partial fundoplication was performed in 86%. At both 1-year and late follow-up, patients reported a significant improvement in ES compared to baseline ( p < 0.05). Of those followed for ≥ 10 years ( n = 44), 82% reported ES < 3 at 1-year ( p < 0.001), and 78% at last follow-up ( p < .001). Of patients who reported treatment success 1-year postoperatively (103/130), 85% continued to report symptomatic relief at last follow-up. Five-year cohort analysis did not show deterioration of dysphagia relief over time. The presence or absence of fundoplication had no impact on long-term outcome ( p > 0.05). Conclusions LHM provides immediate and durable symptomatic relief, with very few patients requiring further therapeutic intervention. Fundoplication does not appear to influence the durability of symptom relief. Treatment success at 1-year is predictive of long-lasting symptomatic relief.
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关键词
Laparoscopic Heller myotomy, Achalasia, Fundoplication, Patient-reported outcomes
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