Synergistic activity between colistin and the ionic liquids 1-methyl-3-dodecylimidazolium bromide, 1-dodecyl-1-methylpyrrolidinium bromide, or 1-dodecyl-1-methylpiperidinium bromide against Gram-negative bacteria.

Walter Florio,Cosmeri Rizzato,Stefano Becherini,Lorenzo Guazzelli,Felicia D'Andrea,Antonella Lupetti

Journal of Global Antimicrobial Resistance（2020）

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摘要

•Colistin and IL 1–3 showed synergistic effect against Gram-negative bacteria•Interaction between colistin and IL 1–3 against E. coli was not synergistic•Synergy between colistin and IL1–3 against P. aeruginosa is bactericidal

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关键词

Ionic liquids,Colistin,Synergy,Checkerboard assay,Outer membrane,Gram-negative bacteria

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