CZ-7, a new derivative of Claulansine F, promotes remyelination induced by cuprizone by enhancing myelin debris clearance.

Sha-Sha Wang,Hao-Zhi Bi,Shi-Feng Chu,Yi-Xiao Dong,Wen-Bin He,Ya-Juan Tian,Ying-Da Zang,Dong-Ming Zhang,Zhao Zhang,Nai-Hong Chen

Brain Research Bulletin（2020）

引用 12|浏览41

暂无评分

摘要

•CZ-7 ameliorates demyelination by CPZ treatment.•CZ-7 enhances the clearance of myelin debris caused by CPZ.•CZ-7 enhances the phagocytic function of microglia.•CZ-7 promotes the change of microglia into M2-polarized phenotype.

查看译文

关键词

CPZ,LFB,MBP,dMBP,CC,CNS,NMO,ADEM,ANHLE,CPM,MS,AD,PD,OPC,EAE,Clau F,SNP,CMC-Na,IHC,IF,IOD,EC

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要